Developments in the field of genetics and genomics are revolutionizing medicine. They are opening the door to the exciting possibility of routine genomic sequencing for average patients and an era of precision medicine. Combining DNA medical test results with a patient’s background, lifestyle, and environment enables them to receive a personalized healthcare plan, including proper diet and exercise.
The Human Genome Project (HGP) was a global, collaborative research program aimed to sequence, map entirely, and understand all human beings’ genes. All our genes together are known as our “genome.” The HGP, which began on October 1, 1990, and was completed in April 2003, gave us the ability to read a complete genetic blueprint of a human being for the first time. This outcome led to the study of genetics – the transmission of genetic traits from one generation to the next. Today, human genetics reinforces all biological fields, including physiology, evolutionary biology, and molecular biology.
Genetics and precision medicine
The practice of medicine is an imprecise science. Clinicians assess a patient’s symptoms and decide what tests to perform to collect more information. They must then decide on symptom causes and a prognosis – whether the patient needs clinical intervention and, if so, which to prescribe. To decide effectively, they might need to evaluate several possible courses of action and factor in all knowledge about the patient. Human physiology is complicated, and sometimes, symptom causes cannot be established. In other instances, there is not enough data to make an entirely informed decision. The guesswork intrinsic in the medical practice diminishes the efficiency of the interventions prescribed.
Genetics contributes significantly to this complexity. Different genetic variations cause conditions that react to other treatments yet share similar symptoms. Without a way to determine the fundamental genetic cause of specific symptoms, it might be impossible to decide on the most effective treatment.
This problem leads us to the importance of combining human genetics and precision medicine. Precision medicine being tailoring illness prevention and management to a specific patient by using their genomic data.
Precision medicine applications to lifestyle and human health
Attempts to reveal the causes of human diseases often recapitulates the nature vs. nurture debate. However, biologists acknowledge that on their own, neither is enough to clarify the molecular progressions that eventually oversee our health. In many instances, the occurrence of a particular mutation or gene means a predisposition to specific disease development. Whether the preference will ultimately manifest as an illness hinges on a multifaceted interaction between human genomes, behavioral, and environmental factors. This awareness has led to multi interdisciplinary genetic approaches to studying disease and health.
One such discipline is nutrigenomics that integrates genomic science and nutrition and, where possible, lifestyle factors, such as alcohol consumption and cigarette smoking. This integration leads to precision nutrition – studying the effects of nutrients on the appearance of an individual’s genetic composition and nutritional factors that protect genes from harm. The concern is the impact that dietary components have on genes, all proteins, and all metabolites. Researchers agree that only certain groups of people will respond well to certain types of diets, for example, while others will be unresponsive or even be harmed.
The primary roles for preventive genetic sequencing (whole-genome sequencing) are as non-invasive screening tests for preventive medicine and as tests to advance diagnostic abilities.
Aside from testing DNA for medication effectiveness in illness prevention and treatment, tests can range from DNA weight loss tests to DNA diet testing, DNA nutrition tests, DNA food tests, DNA health testing, and more. If you are asking why you are eating too much, perhaps you are on a diet not adequate according to your DNA.
OmeHealth by OmeCare
Over the past decade, OmeCare has provided its comprehensive, clinical-grade DNA reports to thousands of doctors and patients to help them make the right health decisions through scientifically validated genetic science.
To keep up with our lives’ fast pace, we often find ourselves adopting unhealthy lifestyles, including consuming nutrient-deficient junk food, not exercising, and more. Perhaps you are trying diets, weightless pills, working with a dietician, have joined a gym, or on medication that is affecting your metabolism, all leaving you asking yourself, “why am I eating so much, and why am I not losing weight?”
One of OmeCare’s cutting-edge DNA tests, OmeHealth, targets the specific areas of nutrition and fitness. The test requires administrating a simple cheek-swab and submitting it to the company. Experts analyze the data and draw up a scientifically-based DNA report detailing your genetic predispositions for consuming macro-nutrients, exercise and training types, food reactions, metabolic health factors, and food reactions. This information will support changes in your behavior and general health. You will also receive information about your metabolic health, vitamin deficiencies, other nutrient deficiencies, and more. You also benefit from nutrition and fitness recommendations to help you lose, gain, or maintain your weight based on your DNA, medical ailments, and preferences.
A personalized diet and exercise plan is just one example of the effective use of genetics for precision medicine!